What is the maximum amount of syntometrine that can be administered in 24 hours?

The maximum amount of syntometrine that is generally accepted for administration in a 24-hour period is typically 10 mL. Syntometrine is a combined preparation of oxytocin and ergometrine, used primarily for the prevention and management of postpartum hemorrhage. The combination of these two medications works effectively to stimulate uterine contractions and reduce the risk of excessive bleeding after childbirth.

Understanding the limits of administration is crucial in midwifery practice, as exceeding recommended dosages can lead to adverse effects, including hypertension and uterine hypertonicity. The guidelines are based on clinical studies and best practices, which provide safety margins for both the patient and the infant.

While lower amounts may be sufficient for certain clinical situations, knowing the maximum allows healthcare providers to manage more severe cases effectively while mitigating risk factors associated with high doses. Thus, specifying the 10 mL limit helps ensure safe usage based on recognized medical standards.